According to the data provided by the Center for Disease Control and Prevention (CDC), there are about 7 million women in the USA (whose age is from 15 to 44) suffering from impaired fecundity. Impaired fecundity is a condition when the person can’t get pregnant or carry a child.
Out of these, at least 1.5 million married women can’t become pregnant after 1 year of unprotected sex with their husbands. One of the main reasons for this is anovulation. Anovulation is an absence of ovulation in females, i.e. when the ovary can’t release a mature egg during menstruation.
To get pregnant, release of egg from the ovary should occur during a woman’s reproductive age. Generic Clomid is the most popular drug for the treatment of anovulatorion in females. When the person suffering from anovulation uses Clomid, this drug decreases the estrogen receptors at hypothalamus, which makes pituitary to release follicle stimulating hormones (FSH) almost in the same way as Gonadotropin releasing hormone (GnRH) does.
Most medical reports state that half of the patients ovulated after the use of cheap Clomid, and 30 % have already became parents. Before ordering Clomid for infertility caused by the lack of ovulation, she must understand that weight loss is an essential part of this treatment, as BMI is closely related to the negative reaction to Clomid.
You shouldn’t use any other ovulation-inducing drugs together with Clomid, as it may increase the possibility of multiple births.
We advise all women suffering from anovulation to keep up the treatment with Clomid women health for about 6 months before thinking about any invasive forms of treatment.
Mechanism of action
An oral medication for treatment of female infertility, Clomid belongs to the non-sterodial ovulatory stimulants. This drugs is very effective in the treatment of female infertility caused by anovulation. Clomid can be solved in methanol or ethanol, as is partially soluble in acetone, chloroform and water. The pill has a color and no odor.
Clomid consists of two geometric isomers. Each pill of cheap Clomid contains 50mg of Clomiphene (the main active substance) and other inactive components like corn starch, lactose, magnesium stearate, pre-gelatinized cornstarch and sucrose.
When taken properly, Clomid has proved to be very successful in the treatment of anovulation. If you start a dose of Clomid 50mg, the active component Clomiphene begin a series of endocrine event with tissues including estrogen receptor, which culminates in a pre-ovulatory gonadotropin leading to the succeeding follicular breakdown.
As the endocrine series begins, the production of pituitary gonadotropins increases, which triggers steroidogenesis and folliculogenesis. This process leads to the increase of the ovarian follicle and changing the level of estradiol and pro-gesterone in the same way as it occur during the normal ovulation.
The two geometric isomers of Clomid Clomiphene, cis zuclomiphene and trans enclomiphene has estrogenic and anti-estrogenic properties.
Pretreatment assessment: – Clomid clomiphene affects the hypothalamus, making the pituitary gland and ovary to enhance FSH levels, thereby completing the infertility treatment in women suffering from anovulation, decreased estrogen level, or reduced level of FSH or with cysts in ovaries.
We recommend all women and their partners to pass the pre-treatment assessment to make sure that Clomid is dutiable for them.
How to start the treatment: – It is essential to understand how and when to start the treatment to get progress.
To achieve maximum effect from Clomid, you should start your treatment with the dose of 50mg on third, fourth or fifth day of your periods. Take one pill of 50mg every day for 5 days.
Some doctors advise single course of progestin drug, such as Provera to trigger menstruation, if the women has irregular period. However, the latest developments in the therapy of infertility with this drug indicate that the pregnancy rate gets higher without causing hemorrhage with medroxyprogesterone, such as Provera.
During a cycle of 28 days, the ovulation happens between 14-19 days of menstruation cycle. To increase the chances of becoming pregnant, you should use ovulation predictor kit for planning your sexual intercourse.
This kit takes the urine sample to forecast ovulation by measuring the amount of luteinizing hormone. The first day of luteinizing hormone surge between 12 pm to 8 am and the next day are the best time to have sex.
Therefore, checking the ovulation in the morning applying OPK may skip day one of LH surge. It is necessary to check the OPK in the afternoon to start the LH surge.
If you don’t wish to use the OPK kit, you should have sex every alternate day for 1 week on the 10th day after the beginning of period. This may require survival of the sperm in the upper genital tract which may reduce the chance in some cases.
If the ovulation doesn’t happen, and you’re still not pregnant after finishing the first month of therapy with generic Clomid, you should buy Clomid online and increase the dose of the drug by 50mg every month until the beginning of ovulation.
If the pregnancy doesn’t happen after ovulation, it makes no use to increase the dose, as there may be some other cause of your infertility. In some cases, the failure to achieve pregnancy may be caused by the man’s infertility.
Studies indicate that pregnancy is achieved during the first six ovulatory cycles when Clomid is used for the treatment of infertility.
The main advantage of generic Clomid is that it costs less compared to the other similar drug, gonadotropin therapy or an artificial fertilization. Therapy with Clomid does not require ultrasound or blood hormone check-up. The risk of serious adverse effect is very low with Clomid that increases the chances of getting pregnant in many women suffering from anovulation or irregular menstruation. The generic of Clomid (Clomiphene) is much cheaper than the brand drug and can be purchased online on our website for effective treatment of infertility.
The use of Clomid may cause multiple pregnancies and ovary enlargement.
Common adverse effects include:
How to increase Clomid effect
If you don’t get pregnant after the treatment with Clomid should undergo X-ray, several blood tests and a semen count test of your partner.
Weight Loss:-BMI must be checked by women with overweight or obesity. Your BMI must not exceed 25.
If the test results are good, and the couple wants to continue the treatment, other actions like weight loss or gain, may be required. A normal BMI minimizes the risk of complications during pregnancy and childbirth.
Weight gain: – Lack of weight also prevents the initiation of ovulation. If your BMI is less than 17, it may enhance the risk of complications.